FR054
FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1].
Product Specifications
CAS Number
[35954-65-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fr054.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(O[C@@H]1[C@]2([H])[C@](OC(C)=N2)([H])O[C@@H]([C@H]1OC(C)=O)COC(C)=O)=O
Molecular Formula
C14H19NO8
Molecular Weight
329.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Francesca Ricciardiello, et al. Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis. Cell Death Dis. 2018 Mar 7;9 (3) :377.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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