TAF1C antibody
Product Specifications
Background
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms
TATA box-binding protein-associated factor RNA polymerase I subunit C|RNA polymerase I-specific TBP-associated factor 110 kDa (TAFI110)|TATA box-binding protein-associated factor 1C (TBP-associated factor 1C)|Transcription initiation factor SL1/TIF-IB subunit C|TAF1C
Gene ID
9013
UniProt
Q15572
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
Target
TAF1C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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