TAB2 antibody
Product Specifications
Background
Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Synonyms
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2|Mitogen-activated protein kinase kinase kinase 7-interacting protein 2|TAK1-binding protein 2 (TAB-2)|TGF-beta-activated kinase 1-binding protein 2|TAB2|KIAA0733|MAP3K7IP2
Gene ID
23118
UniProt
Q9NYJ8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Target
TAB2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, WB, FC, IP
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
77 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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