SYTL2 antibody
Product Specifications
Background
Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine(PS) and phosphatidylinositol-4,5-bisphosphate(PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
Synonyms
Synaptotagmin-like protein 2|Breast cancer-associated antigen SGA-72M|Exophilin-4|SYTL2|KIAA1597|SGA72M|SLP2|SLP2A
Gene ID
54843
UniProt
Q9HCH5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
synaptotagmin-like 2
Target
SYTL2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100-105 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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