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SYTL2 antibody

Product Specifications

Background

Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca (2+) while binding to PIP2 is Ca (2+) insensitive.

Synonyms

Synaptotagmin-like protein 2|Breast cancer-associated antigen SGA-72M|Exophilin-4|SYTL2|KIAA1597|SGA72M|SLP2|SLP2A

Gene ID

54843

UniProt

Q9HCH5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synaptotagmin-like 2

Target

SYTL2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Cell Division and Proliferation

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

100-105 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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