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SYNM antibody

Product Specifications

Background

Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.

Synonyms

Synemin|Desmuslin|SYNM|DMN|KIAA0353|SYN

Gene ID

23336

UniProt

O15061

Host

Rabbit

Reactivity

Human

Immunogen

Synemin, intermediate filament protein

Target

SYNM

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

175 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

Immunogen Sequence

Peptide, C-terminal

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