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SUMO2/3 antibody

Product Specifications

Background

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

Small ubiquitin-related modifier 2 (SUMO-2)|HSMT3|SMT3 homolog 2|SUMO-3|Sentrin-2|Ubiquitin-like protein SMT3B (Smt3B)|SUMO2|SMT3B|SMT3H2

Gene ID

6613

UniProt

P61956

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

SMT3 suppressor of mif two 3 homolog 2

Target

SUMO2/3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Epigenetics, Cell Division and Proliferation, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

11-14 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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