STXBP2 antibody
Product Specifications
Background
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Synonyms
Syntaxin-binding protein 2|Protein unc-18 homolog 2 (Unc18-2)|Protein unc-18 homolog B (Unc-18B)|STXBP2|UNC18B
Gene ID
6813
UniProt
Q15833
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
syntaxin binding protein 2
Target
STXBP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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