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STXBP1 antibody

Product Specifications

Background

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Synonyms

Syntaxin-binding protein 1|MUNC18-1|N-Sec1|Protein unc-18 homolog 1 (Unc18-1) |Protein unc-18 homolog A (Unc-18A) |p67|STXBP1|UNC18A

Gene ID

6812

UniProt

P61764

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Syntaxin binding protein 1

Target

STXBP1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

65-68 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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