STK36 antibody
Product Specifications
Background
Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483) . Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483) . GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483) . Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity) . Essential for construction of the central pair apparatus of motile cilia.
Synonyms
Serine/threonine-protein kinase 36|Fused homolog|STK36|KIAA1278
Gene ID
27148
UniProt
Q9NRP7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Serine/threonine kinase 36, fused homolog (Drosophila)
Target
STK36
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
144 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx431694 200 µL
Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) Antibody
Sign In for Pricing
View Details 
V2640-02X-PE 100 µL
Von Hippel-Lindau Protein (vHL) (BSA & Azide Free) (PE) discontinued
Sign In for Pricing
View Details