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SRGAP1 antibody

Product Specifications

Background

GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

Synonyms

SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) |Rho GTPase-activating protein 13|SRGAP1|ARHGAP13|KIAA1304

Gene ID

57522

UniProt

Q7Z6B7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

SLIT-ROBO Rho GTPase activating protein 1

Target

SRGAP1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Neuroscience, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

130 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

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