SRGAP1 antibody
Product Specifications
Background
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
Synonyms
SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) |Rho GTPase-activating protein 13|SRGAP1|ARHGAP13|KIAA1304
Gene ID
57522
UniProt
Q7Z6B7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SLIT-ROBO Rho GTPase activating protein 1
Target
SRGAP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
130 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
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