SREBF1 antibody
Product Specifications
Background
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity) . Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') . Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3') .
Synonyms
Sterol regulatory element-binding protein 1 (SREBP-1) |Class D basic helix-loop-helix protein 1 (bHLHd1) |Sterol regulatory element-binding transcription factor 1|Processed sterol regulatory element-binding protein 1 Alternative names: Transcription factor SREBF1|SREBF1|BHLHD1|SREBP1
Gene ID
6720
UniProt
P36956
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Sterol regulatory element binding transcription factor 1
Target
SREBF1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Neuroscience, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
125 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP
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