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SREBF1 antibody

Product Specifications

Background

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity) . Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') . Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3') .

Synonyms

Sterol regulatory element-binding protein 1 (SREBP-1) |Class D basic helix-loop-helix protein 1 (bHLHd1) |Sterol regulatory element-binding transcription factor 1|Processed sterol regulatory element-binding protein 1 Alternative names: Transcription factor SREBF1|SREBF1|BHLHD1|SREBP1

Gene ID

6720

UniProt

P36956

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Sterol regulatory element binding transcription factor 1

Target

SREBF1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IP

Field of Research

Neuroscience, Cardiovascular, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

125 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IP

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