SPPL2A antibody
Product Specifications
Background
SPPL2A (Signal peptide peptidase-like 2A) is also named as IMP3 (Intramembrane protease 3), PSL2 (Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A (SPPL2a) is localised in lysosomes/late endosomes (PMID:21896273) .
Synonyms
Signal peptide peptidase-like 2A (SPP-like 2A, SPPL2a) |Intramembrane protease 3 (IMP-3) |Presenilin-like protein 2|SPPL2A|IMP3|PSL2
UniProt
Q8TCT8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Signal peptide peptidase-like 2A
Target
SPPL2A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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