SPPL2A antibody

Product Specifications

Background

SPPL2A (Signal peptide peptidase-like 2A) is also named as IMP3 (Intramembrane protease 3), PSL2 (Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A (SPPL2a) is localised in lysosomes/late endosomes (PMID:21896273) .

Synonyms

UniProt

Q8TCT8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Signal peptide peptidase-like 2A

Target

SPPL2A

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

58 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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