SOX17 antibody
Product Specifications
Background
Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity) .
Synonyms
Transcription factor SOX-17|SOX17
Gene ID
64321
UniProt
Q9H6I2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SRY (sex determining region Y) -box 17
Target
SOX17
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Stem Cells, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
300-414aa
Curated Selection
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