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SOX17 antibody

Product Specifications

Background

Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity) .

Synonyms

Transcription factor SOX-17|SOX17

Gene ID

64321

UniProt

Q9H6I2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

SRY (sex determining region Y) -box 17

Target

SOX17

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Epigenetics, Stem Cells, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

44 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

Immunogen Sequence

300-414aa

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