SOS1 antibody
Product Specifications
Background
Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579) . Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331) . Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity) .
Synonyms
Son of sevenless homolog 1 (SOS-1) |SOS1
Gene ID
6654
UniProt
Q07889
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Son of sevenless homolog 1
Target
SOS1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Cancer, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
180 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
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