SOD2 antibody
Product Specifications
Background
SOD2 (superoxide dismutase 2, mitochondrial) is also named as IPOB, MNSOD, SODM, Mn-SOD and belongs to the iron/manganese superoxide dismutase family. It is a marker of mitochondria, which is restricted to the perinuclear area in a cell with aggregate formation of mutant SOD1 (PMID:12659845) . It functions as the first line of antioxidant defense against highly reactive superoxide radicals and it appears to be early predictors for survival in septic patients with with MIF (PMID:20863520) . It has 2 isoforms with the molecular weight of 25 kDa and 21 kDa.
Synonyms
Superoxide dismutase [Mn], mitochondrial|SOD2
Gene ID
6648
UniProt
P04179
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Superoxide dismutase 2, mitochondrial
Target
SOD2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC, IP
Field of Research
Neuroscience, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
25 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC, IP
Curated Selection
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