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SNRPF antibody

Product Specifications

Background

Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.

Synonyms

Small nuclear ribonucleoprotein F (snRNP-F)|Sm protein F (Sm-F, SmF)|SNRPF|PBSCF

Gene ID

6636

UniProt

P62306

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

small nuclear ribonucleoprotein polypeptide F

Target

SNRPF

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, FC

Field of Research

Neuroscience, Metabolism, Epigenetics

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

10 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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