SNRPD3 antibody
Product Specifications
Background
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.
Synonyms
Small nuclear ribonucleoprotein Sm D3 (Sm-D3)|snRNP core protein D3|SNRPD3
Gene ID
6634
UniProt
P62318
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
small nuclear ribonucleoprotein D3 polypeptide 18kDa
Target
SNRPD3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism, Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
14 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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