SNCB antibody

Product Specifications

Background

Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA) -stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

Synonyms

Beta-synuclein|SNCB

Gene ID

6620

UniProt

Q16143

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synuclein, beta

Target

SNCB

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF, FC

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:10-1:100; IF: 1:10-1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

14-18 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF, FC

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