SMYD3 antibody
Product Specifications
Background
Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di-and tri-methylation, but not monomethylation(PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4(PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex(PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences(PubMed:15235609).
Synonyms
Histone-lysine N-methyltransferase SMYD3|SET and MYND domain-containing protein 3|Zinc finger MYND domain-containing protein 1|SMYD3|ZMYND1|ZNFN3A1
Gene ID
64754
UniProt
Q9H7B4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SET and MYND domain containing 3
Target
SMYD3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IP, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
42-45 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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