ACTA2 antibody
Product Specifications
Background
ACTA2, also named as a-SMA, AAT6; ACTSA belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) . The immunogen of this antibody is a specific domain of ACTA2. This antibody stains the aorta only.
Synonyms
Actin, aortic smooth muscle|Alpha-actin-2|Cell growth-inhibiting gene 46 protein|Actin, aortic smooth muscle, intermediate form|ACTA2|ACTSA|ACTVS|alpha-Smooth Muscle Actin|α-SMA
Gene ID
59
UniProt
P62736
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Actin, alpha 2, smooth muscle, aorta
Target
ACTA2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Epigenetics, Cancer, Signal Transduction, Metabolism, Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
42 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF
Immunogen Sequence
Peptide
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