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ACTA2 antibody

Product Specifications

Background

ACTA2, also named as a-SMA, AAT6; ACTSA belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) . The immunogen of this antibody is a specific domain of ACTA2. This antibody stains the aorta only.

Synonyms

Actin, aortic smooth muscle|Alpha-actin-2|Cell growth-inhibiting gene 46 protein|Actin, aortic smooth muscle, intermediate form|ACTA2|ACTSA|ACTVS|alpha-Smooth Muscle Actin|α-SMA

Gene ID

59

UniProt

P62736

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Actin, alpha 2, smooth muscle, aorta

Target

ACTA2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, WB, IF

Field of Research

Epigenetics, Cancer, Signal Transduction, Metabolism, Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

42 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC, WB, IF

Immunogen Sequence

Peptide

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