MIEF1 antibody
Product Specifications
Background
Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa (also called mitochondrial elongation factor 1, MIEF1) . MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.
Synonyms
Mitochondrial dynamics protein MIEF1|Mitochondrial dynamics protein of 51 kDa|Mitochondrial elongation factor 1|Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like (SMCR7-like protein) |MIEF1|MID51|SMCR7L
Gene ID
54471
UniProt
Q9NQG6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Smith-Magenis syndrome chromosome region, candidate 7-like
Target
MIEF1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
49 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP
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