SMC3 antibody
Product Specifications
Background
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Synonyms
Structural maintenance of chromosomes protein 3 (SMC protein 3, SMC-3) |Basement membrane-associated chondroitin proteoglycan (Bamacan) |Chondroitin sulfate proteoglycan 6|Chromosome-associated polypeptide (hCAP) |SMC3|BAM|BMH|CSPG6|SMC3L1
Gene ID
9126
UniProt
Q9UQE7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Structural maintenance of chromosomes 3
Target
SMC3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Cell Division and Proliferation, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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