SMARCB1 antibody
Product Specifications
Background
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.
Synonyms
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1|BRG1-associated factor 47 (BAF47) |Integrase interactor 1 protein|SNF5 homolog (hSNF5) |SMARCB1|BAF47|INI1|SNF5L1
Gene ID
6598
UniProt
Q12824
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Target
SMARCB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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