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SMARCAL1 antibody

Product Specifications

Background

ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A(RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.

CAS Number

9007-83-4

Synonyms

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1|HepA-related protein (hHARP)|Sucrose nonfermenting protein 2-like 1|SMARCAL1|HARP

Gene ID

50485

UniProt

Q9NZC9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1

Target

SMARCAL1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

106 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

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