SMARCAL1 antibody
Product Specifications
Background
ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A(RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.
Synonyms
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1|HepA-related protein (hHARP)|Sucrose nonfermenting protein 2-like 1|SMARCAL1|HARP
Gene ID
50485
UniProt
Q9NZC9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Target
SMARCAL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
106 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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