Slc4a8 antibody
Product Specifications
Background
Mediates electroneutral sodium-and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity(By similarity).
Synonyms
Electroneutral sodium bicarbonate exchanger 1|Electroneutral Na+-driven Cl-HCO3 exchanger|Solute carrier family 4 member 8|k-NBC3|Slc4a8|Ndcbe1
Gene ID
315311
UniProt
Q6RVG2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
solute carrier family 4, sodium bicarbonate cotransporter, member 8
Target
Slc4a8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
121 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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