SLC17A5 antibody
Product Specifications
Background
Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential-dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed and secreted in saliva.
Synonyms
Sialin|H(+)/nitrate cotransporter|H(+)/sialic acid cotransporter (AST)|Membrane glycoprotein HP59|Solute carrier family 17 member 5|Vesicular excitatory amino acid transporter (VEAT)|SLC17A5
Gene ID
26503
UniProt
Q9NRA2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
solute carrier family 17(anion/sugar transporter), member 5
Target
SLC17A5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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