SLC11A2 antibody
Product Specifications
Background
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
Synonyms
Natural resistance-associated macrophage protein 2 (NRAMP 2)|Divalent cation transporter 1|Divalent metal transporter 1 (DMT-1)|Solute carrier family 11 member 2|SLC11A2|DCT1|DMT1|NRAMP2
Gene ID
4891
UniProt
P49281
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
solute carrier family 11(proton-coupled divalent metal ion transporters), member 2
Target
SLC11A2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60-70, 75-100 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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