SIX5 antibody
Product Specifications
Background
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter(By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3(By similarity).
Synonyms
Homeobox protein SIX5|DM locus-associated homeodomain protein|Sine oculis homeobox homolog 5|SIX5|DMAHP
Gene ID
147912
UniProt
Q8N196
Host
Rabbit
Reactivity
Human
Immunogen
SIX homeobox 5
Target
SIX5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IP
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100-105 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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