SIX5 antibody
Product Specifications
Background
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity) . Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity) .
Synonyms
Homeobox protein SIX5|DM locus-associated homeodomain protein|Sine oculis homeobox homolog 5|SIX5|DMAHP
Gene ID
147912
UniProt
Q8N196
Host
Rabbit
Reactivity
Human
Immunogen
SIX homeobox 5
Target
SIX5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IP
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100-105 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IP
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