SHANK1 antibody
Product Specifications
Background
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
Synonyms
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) |Somatostatin receptor-interacting protein (SSTR-interacting protein, SSTRIP) |SHANK1
Gene ID
50944
UniProt
Q9Y566
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SH3 and multiple ankyrin repeat domains 1
Target
SHANK1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
250-300 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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