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SH3BP5 antibody

Product Specifications

Background

Inhibits the auto-and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.

Synonyms

SH3 domain-binding protein 5 (SH3BP-5) |SH3 domain-binding protein that preferentially associates with BTK|SH3BP5|SAB

Gene ID

9467

UniProt

O60239

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

SH3-domain binding protein 5 (BTK-associated)

Target

SH3BP5

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

47 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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