SH3BP5 antibody
Product Specifications
Background
Inhibits the auto-and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
Synonyms
SH3 domain-binding protein 5 (SH3BP-5) |SH3 domain-binding protein that preferentially associates with BTK|SH3BP5|SAB
Gene ID
9467
UniProt
O60239
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SH3-domain binding protein 5 (BTK-associated)
Target
SH3BP5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
47 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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