SESN3 antibody
Product Specifications
Background
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562) . May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity) . This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity) .
Synonyms
Sestrin-3|SESN3|SEST3
Gene ID
143686
UniProt
P58005
Host
Rabbit
Reactivity
Human
Immunogen
Sestrin 3
Target
SESN3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
51-59 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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