SEC61A1 antibody
Product Specifications
Background
The SEC61 complex is a major component of the endoplasmic reticulum (ER) translocation site (PMID: 7720858) . This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER.
Synonyms
Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1) |SEC61A1|SEC61A
UniProt
P61619
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Sec61 alpha 1 subunit
Target
SEC61A1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
52 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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