SCUBE3 antibody
Product Specifications
Background
Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
CAS Number
9007-83-4
Synonyms
Signal peptide, CUB and EGF-like domain-containing protein 3|SCUBE3|CEGF3
Gene ID
222663
UniProt
Q8IX30
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
signal peptide, CUB domain, EGF-like 3
Target
SCUBE3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Cardiovascular, Developmental biology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
130 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
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