SCN10A antibody

Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.

Sodium channel protein type 10 subunit alpha|Peripheral nerve sodium channel 3 (PN3, hPN3) |Sodium channel protein type X subunit alpha|Voltage-gated sodium channel subunit alpha Nav1.8|SCN10A