SASS6 antibody

Product Specifications

Background

Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification (PubMed:22020124) .

Synonyms

Spindle assembly abnormal protein 6 homolog (HsSAS-6) |SASS6|SAS6

Gene ID

163786

UniProt

Q6UVJ0

Host

Rabbit

Reactivity

Human

Immunogen

Spindle assembly 6 homolog

Target

SASS6

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Cell Division and Proliferation

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

74 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

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