S100A12 antibody

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

Protein S100-A12|CGRP|Calcium-binding protein in amniotic fluid 1 (CAAF1) |Calgranulin-C (CAGC) |Extracellular newly identified RAGE-binding protein (EN-RAGE) |Migration inhibitory factor-related protein 6 (MRP-6, p6) |Neutrophil S100 protein|S100 calcium-binding protein A12|Calcitermin|S100A12