RNF213 antibody
Product Specifications
Background
E3 ubiquitin-protein ligase involved in angiogenesis (PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547) . Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression (PubMed:26766444) . Also has ATPase activity (PubMed:24658080, PubMed:26126547) .
Synonyms
E3 ubiquitin-protein ligase RNF213|ALK lymphoma oligomerization partner on chromosome 17|E3 ubiquitin-lipopolysaccharide ligase RNF213|Mysterin|RING finger protein 213|RNF213|ALO17|C17orf27|KIAA1554|KIAA1618|MYSTR
Gene ID
57674
UniProt
Q63HN8
Host
Rabbit
Reactivity
Human
Immunogen
Ring finger protein 213
Target
RNF213
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC
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