RNF2 antibody
Product Specifications
Background
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Synonyms
E3 ubiquitin-protein ligase RING2|Huntingtin-interacting protein 2-interacting protein 3 (HIP2-interacting protein 3)|Protein DinG|RING finger protein 1B (RING1b)|RING finger protein 2|RING finger protein BAP-1|RING-type E3 ubiquitin transferase RING2|RNF2|BAP1|DING|HIPI3|RING1B
Gene ID
6045
UniProt
Q99496
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ring finger protein 2
Target
RNF2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Epigenetics, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
39 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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