RNASEH1 antibody
Product Specifications
Background
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed:10497183) . Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly (A) site and behind the elongating RNAp II (PubMed:21700224) .
Synonyms
Ribonuclease H1 (RNase H1) |Ribonuclease H type II|RNASEH1|RNH1
Gene ID
246243
UniProt
O60930
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ribonuclease H1
Target
RNASEH1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
32 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP
Immunogen Sequence
1-286aa, full length
Curated Selection
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