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RIN1 antibody

Product Specifications

Background

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Synonyms

Ras and Rab interactor 1|Ras inhibitor JC99|Ras interaction/interference protein 1|RIN1

Gene ID

9610

UniProt

Q13671

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Ras and Rab interactor 1

Target

RIN1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Neuroscience, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

90 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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