REC8 antibody
Product Specifications
Background
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity) .
Synonyms
Meiotic recombination protein REC8 homolog|Cohesin Rec8p|REC8|REC8L1
Gene ID
9985
UniProt
O95072
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
REC8 homolog (yeast)
Target
REC8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cell Division and Proliferation, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85-95 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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