RBPMS antibody
Product Specifications
Background
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).
Synonyms
RNA-binding protein with multiple splicing (RBP-MS)|Heart and RRM expressed sequence (Hermes)|RBPMS|HERMES
Gene ID
11030
UniProt
Q93062
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RNA binding protein with multiple splicing
Target
RBPMS
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, FC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
28-30 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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