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RBM15 antibody

Product Specifications

Background

May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.

Synonyms

RNA-binding protein 15|One-twenty two protein 1|RNA-binding motif protein 15|RBM15|OTT|OTT1

Gene ID

64783

UniProt

Q96T37

Host

Mouse

Reactivity

Human

Immunogen

RNA binding motif protein 15

Target

RBM15

Clonality

Monoclonal

Isotype

IgG1

Applications

ELISA, WB, IHC, IF, IP

Field of Research

Stem Cells

Purification

Protein A+G purification

Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:200-1:800; IF: 1:10-1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

107 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

6B1

Tested Applications

ELISA, WB, IHC, IF, IP

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