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RANBP9 antibody

Product Specifications

Background

May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA(By similarity).

Synonyms

Ran-binding protein 9 (RanBP9)|BPM-L|BPM90|Ran-binding protein M (RanBPM)|RanBP7|RANBP9|RANBPM

Gene ID

10048

UniProt

Q96S59

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

RAN binding protein 9

Target

RANBP9

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

80-90 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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